Job Posting: Bioinformatician
Position/Business Title:
Bioinformatician (job posting #9393)
Position Summary:
This individual will analyse diverse sets of high throughput genomic data derived from clinical breast and ovarian tumours. Focused on next-generation sequencing of tumours, the individual will execute routine analyses of data as they emerge and collate results into reportable databases to investigators. The position will focus on characterizing mutations in different cancer subtypes and determining molecular heterogeneity of large cohorts of patients to enable subtype-specific therapies for cancer patients. In addition, project and data management will be a component of this position.
Organizational Status:
Working independently and reporting to the Principal Investigator in Molecular Oncology or designate, and in conjunction with investigators within the BCCA, UBC and internationally.
Work Performed:
- Provides expertise in the planning and development and application of novel algorithms and statistical models
- Performs algorithmic and statistical analyses on next generation sequencing data, Affymetrix, SNP 6.0 array data
- Contributes interpretive analysis on large data sets in the context of affected genes and pathways
- Contributes to writing scientific manuscripts
- Performs other duties as related to the position such as data and project management to ensure data is being processed in an efficient and timely manner
Supervision Received:
Supervision from Principal Investigator or designate. Results reviewed for achievement of overall objectives.
Supervision Given:
May manage undergraduate, research and bioinformatician trainees.
Education/Work Experience:
- Post-graduate degree in one of the following:
- bioinformatics, biostatistics, computer science (with some complementary background in molecular biology/genetics), statistics or genetics (with significant computational expertise)
- Minimum of 5 years related experience working in a research or corporate environment or the equivalent combination of education and experience.
- Strong knowledge of Unix/Linux operating system
- Programming/scripting skills in at least two of the following:
- C/C++, Java, Perl
- Expertise with at least one of the following:
- Matlab, R
- Working knowledge of SQL/relational databases
- Familiarity with human genome databases such as Ensembl, UCSC genome browser, NCBI
- Familiarity with parallel computing environments (Linux clusters, SunGridEngine, OpenPBS, etc…)
- Experience with bioinformatics tools such as Bioconductor, BioPerl/BioJava, BLAST considered an asset
- Experience in development of algorithms/machine learning/statistical models for bioinformatics considered an asset
- Ability to work in different locations as required.
Please send a CV and cover letter to cennis [at] bccrc [dot] ca, quoting job posting #9393