Research
Breast cancer genome sequencing
Discovery of novel gene mutations
METABRIC
Molecular classification of breast cancer subtypes
Screening the human genome for genes involved in breast cancer
Discovery of novel gene-gene and gene-drug interactions
Dissecting genetic heterogeneity within breast tumours
Identification and characterisation of tumour cell subpopulations
Mammographic density and columnar cell lesions of the breast
Investigation of the connection between common breast cell abnormalities and the higher risk of tumour development in dense breast tissue
Characterisation of normal and cancerous mammary stem cells
Discovery of genes involved in stem cell proliferation and differentiation
Kisspeptins and GPR54 in breast cancer metastasis
Characterisation of the role of GPR54 in breast cancer progression
Single cell genomics
Development of novel methods for single cell analysis
Induced pluripotent stem (iPS) cells
Development of novel methods to help move iPS cells into the clinic