Publications
Research
Croteau E, Lavallée E, Labbe SM, Hubert L, Pifferi F, Rousseau JA, Cunnane SC, Carpentier AC Lecomte R, Bénard F. Image-derived input function in dynamic human PET/CT: methodology and validation with 11C-acetate and 18F-fluorothioheptadecanoic acid in muscle and 18F-fluorodeoxyglucose in brain. Eur J Nucl Med Mol Imaging 2010 DOI 10.1007/s00259-010-1443-z
Guérin B, Dumulon-Perreault V, Tremblay MC, Mohand S, Fournier P, Dubuc C, Authier S, Bénard F. [Lys(DOTA)4]BVD15, a Novel and Potent Neuropeptide Y Analog Designed for Y1 Receptor-Targeted Breast Tumor Imaging. Bioorganic and Medicinal Chemistry Letters 2010; 20: 950-953
Worsley DF, Wilson DC, Powe JE, Bénard F. Impact of F-18 Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography on Oncologic Patient Management: First 2 Year’s Experience at a Single Canadian Cancer Center. Can Assoc Radiol J 2010 61(1):13-8
Guérin B, Ait-Mohand S, Tremblay MC, Dumulon-Perreault V, Fournier P, Bénard F. Total Solid-Phase Synthesis of NOTA-Functionalized Peptides for PET Imaging. Org Lett. 2010 12:280-3
Arab AW, Echavé V, Sirois M, Bénard F, Gomes MM. Primary myxoid sarcoma of the pleura: a case report. Canadian Journal of Surgery 2009; 52:E93-E94
Beauregard JM, Croteau E, Ahmed N, van Lier JE, Bénard F. Assessment of human biodistribution and dosimetry of 4-fluoro-11b-methoxy-16a-[18F]fluoroestradiol using serial whole-body PET/CT acquisitions. J Nucl Med 2009 50(1):100-7
Ménard SL, Ci X, Frisch F, Normand-Lauzière F, Cadorette J, Ouellet R, Van Lier JE, Bénard F, Bentourkia M, Lecomte R, Carpentier AC. Mechanism of Reduced Myocardial Glucose Utilization During Acute Hypertriglyceridemia in Rats. Mol Imaging Biol. 2009 11(1):6-14
Tremblay S, Ouellet R, Bénard F, Cunnane SC. Automated synthesis of 11C-beta-hydroxybutyric acid by enzymatic conversion of 11C-acetoacetic acid using beta-hydroxybutyrate dehydrogenase. J Labelled Comp Radiopharm 2008; 51: 242-245
Soucy-Faulkner A, Rousseau JA, Langlois R, Bérard V, Lecomte R, Bénard F, van Lier JE. Copper-64 labeled sulfophthalocyanines for positron emission tomography (PET) imaging in tumor bearing rats. J porphyrins and phthalocyanines 2008; 12: 49-53
Bénard F, Ahmed N, Beauregard JM, Rousseau J, Aliaga A, Dubuc C, Croteau E, van Lier JE. [F-18]Fluorinated estradiol derivatives for estrogen receptor imaging: impact of substituents, formulation and specific activity on the biodistribution in breast tumor bearing mice. Eur J Nucl Med Mol Imaging 2008; 35: 1473-1479.
Authier S, Tremblay S, Dumulon V, Dubuc C, Ouellet R, Lecomte R, Cunnane SC, Bénard F. [11C]Acetoacetate utilization by breast and prostate tumors: A PET and biodistribution study in mice. Mol Imaging Biol 2008; 10(4):217-23.
Dubuc C, Langlois R, Bénard F, Cauchon N, Klarskov K, Tone P, van Lier JE. Targeting gastrin-releasing peptide receptors of prostate cancer cells for photodynamic therapy with a phthalocyanine-bombesin conjugate. Bioorganic and Medicinal Chemistry Letters 2008; 18:2424-2427.
Beanlands RSB, Nichol G, Huszti E, Humen D, Racine N, Freeman M, Gulenchyn KY, Bénard F, Garrard L, Ruddy T, deKemp R, Hendry P, Iwanochko RM and the PARR2 Investigators. F-18 Fluorodeoxyglucose positron emission tomography imaging-guided management of patients with coronary disease and severe left ventricular dysfunction: a randomized, controlled trial (PARR-2). J Am Coll Cardiol 2007; 50: 2002-2012.
Aliaga A, Rousseau J, Cadorette J, Croteau E, van Lier JE, Lecomte R, Bénard F. A small animal PET study of the effect of chemotherapy and hormonal therapy on the uptake of FDG in murine models of breast cancer. Molecular Imaging and Biology 2007; 9: 144-150.
Ahmed N, Langlois R, Bénard F, van Lier JE. Automated synthesis of 4-fluoro-11β-methoxy-16αfluoroestradiol (4F-M[18F]FES) for estrogen receptor imaging with positron emission tomography. Nucl Med Biol 2007; 34: 459-464.
Tremblay S, Ouellet R, Rodrigue S, Langlois R, Bénard F, Cunnane S. Automated synthesis of 11C-Acetoacetate, a key alternate brain fuel to glucose. Applied Radiation and Isotopes 2007;65: 934-940.
Beauregard JM, Croteau E, Ahmed N, Ouellette R, van Lier JE, Bénard F. A simple method for effective specific activity determination of estrogen receptor-binding radiopharmaceuticals. Nucl Med Biol 2007; 34: 325-329.
Turcotte E, Leblanc M, Carpentier A, Bénard F. Use of i.v. insulin and delayed 18F-FDG injection to reduce blood glucose levels for PET imaging of diabetic patients. Molr Imaging Biol 2006; 8:348-354.
Prévost S, Boucher L, Larivée P, Boileau R, Bénard F. Evaluation of PET based prognostic factors in non small cell lung cancer. J Nucl Med 2006; 47:559-65.
Bénard F, Turcotte E. Imaging breast cancer with single photon computed tomography and positron emission tomography. Breast Cancer Research 2005; 7:153-162.
Croteau E, Bénard F, Bentourkia M, Rousseau J, Paquette M, Lecomte R. Quantitative myocardial perfusion and coronary reserve in rats with 13N-Ammonia and small animal PET : impact of anesthesia and pharmacological stress agents. J Nucl Med 2004; 45: 1924-1930.
Seimbille Y, Bénard F, Rousseau J, Pépin E, Aliaga A, Tessier G, van Lier JE. Impact on estrogen receptor binding and target tissue uptake of [18F]fluorine substitution at the 16a-position of fulvestrant (Faslodex; ICI 182,780). Nucl Med Biol 2004; 31: 691-698.
Aliaga A, Rousseau J, Ouellette R, Cadorette J, van Lier JE, Lecomte R, Bénard F. Breast cancer models to study the expression of estrogen receptors with small animal PET imaging. Nucl Med Biol 2004; 31: 761-770.
Boucher L, Rodrigue S, Lecomte R, Bénard F. Respiratory gated 3D PET of the thorax : Feasibility and initial results. J Nucl Med 2004; 45 : 214-219.
Reviews
Bénard F. The challenges of improving breast cancer outcome with diagnostic imaging techniques. Oncology (Williston Park) 2009 23(3):264, 266
Beauregard JM, Turcotte E, Bénard F. Steroid receptor imaging in breast cancer. PET Clinics of North America 2006; 1:51-70.