Datasets

Supplemental Data:

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups (Curtis, Shah et al, Nature 2012)

  1. Supplementary Information (24.1M)
    This file contains Supplementary Methods (see Contents for more details), Supplementary References, Supplementary Figures 1-39 and legends for Supplementary Tables 1-47 (see separate zipped files for tables).
  1. Supplementary Tables 1 (20.6M)
    This file contains Supplementary Tables 1-6.
  2. Supplementary Tables 2 (18.3M)
    This file contains Supplementary Tables 7-16.
  3. Supplementary Tables 3 (9.8M)
    This file contains Supplementary Tables 17-31.
  4. Supplementary Tables 4 (26.6M)
    This file contains Supplementary Tables 32-35.
  5. Supplementary Tables 5 (14.4M)
    This file contains Supplementary Tables 36-41.
  6. Supplementary Tables 6 (28.3M)
    This file contains Supplementary Tables 42-47.

The clonal and mutational evolution spectrum of primary triple-negative breast cancers (Shah et al, Nature 2012)

  1. Supplementary Information (22M)
    This file contains legends for Supplementary Figures 1-12 (see pages 2-5), Supplementary Figures 1-12 (see pages 6-127), Supplementary Methods with additional references (see pages 128-140) and legends for Supplementary Tables 1-17 with additional references (see pages 142-145).
  1. Supplementary Data (4.9M)
    This file contains Supplementary Tables 1-17.

Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution (Shah et al, Nature 2009)

Supplementary Information

This file contains Supplementary Methods and Data and Supplementary References.

Supplementary Information – Download PDF file (267KB)

Supplementary Information

This file contains Supplementary Figures S1-S9 with Legends together with the Legends for Supplementary Tables in S1-S12 (see file s3).

Supplementary Information – Download PDF file (2.9MB)

Supplementary Tables

This files contains Supplementary Tables S1-S12 (see file s2 for Legends).

Supplementary Tables – Download Excel file (6.6MB)

Supplementary Data

This Supplemental Appendix file contains inferring SNVs from aligned reads using a Bayesian mixture model.

Supplementary Data – Download PDF file (1.9MB)

Raw sequence reads for the genome and transcriptome (RNA-seq) are available by tiered access at the European Genome-Phenome Archive under accession number: EGAS00000000054

Trace files for RNA-editing analysis as described in Shah et al (2009) “Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution”. [DOWNLOAD]

UCSC bed file containing predicted alternative splicing events mentioned in Shah et al (2009) “Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution”. Nature [DOWNLOAD]

Entosis movie using histone 2B venus to mark nuclei. [DOWNLOAD]