General Inquiries
If you are interested in pursuing graduate or postdoctoral training in The Department of Molecular Oncology, please send a CV and cover letter to CareersMolOnc [at] bccrc [dot] ca.
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Join a dynamic cancer genomics and computational biology/bioinformatics research team at the BC Cancer Agency, Vancouver, BC CANADA
The following five positions are immediately available in the Computational Biology Lab of Dr. Sohrab Shah (compbio.bccrc.ca):
….. to implement algorithms and statistical models for the purposes of analysing high throughput cancer genomics data. The position will entail developing robust, efficient and fault tolerant software in a Linux environment using bioinformatics libraries available in the C++/C, Python and R programming languages. This work will be used to support leading edge research in sequencing cancer genomes and identifying causal mutations in breast and ovarian cancers and lymphomas. The end product(s) will be distributed to computational biology groups worldwide working in the field of cancer genomics. The programmer will interact with other programmers, database developers, bioinformaticians, graduate students, post-doctoral fellows and clinical collaborators in an immersive and dynamic multi-disciplinary research environment.
….. to analyse and interpret diverse sets of high throughput genomic data derived from clinical breast and ovarian tumours. Focused on next-generation sequencing datasets, the individual will execute advanced analyses of whole genome, whole transcriptome and other sequencing data and collate results into reportable databases to investigators. The position will focus on characterizing mutations in different cancer subtypes and determining molecular heterogeneity of large cohorts of patients to enable subtype-specific therapies for cancer patients. In addition, project and data management will be a component of this position.
….. to support data management of high dimensional and complex datasets. Focused on next-generation sequencing datasets, the individual will develop robust relational database solutions to the need for efficient storage, retrieval and interfacing with human-genome level data from cancer patient tumour samples. The database developer will interface with a team of software developers, bioinformaticians and principal investigators to ensure enterprise level integrity of genomic data. The position will involve facilitating tight integration of genomic and clinical databases from breast and ovarian cancer research groups. Solutions will be deployed broadly in the BC Cancer Agency.
Post-doctoral researcher (2013SS05)
….. to lead key research projects ongoing in the lab of Dr. Sohrab Shah. The PDF should hold a PhD degree in bioinformatics, computer science, statistics or molecular biology and possess exceptional computational skills. The research will focus on one or more of the following topics, all related to analysis of next generation whole genome sequencing data: i) quantifying and modeling tumour evolution; ii) germline genetics and hereditary cancer; iii) alternative splicing in cancer; iv) the mutational landscape of triple negative breast cancer. The PDF will design and carry out experiments to address key questions in the above topics and lead the writing of scientific manuscripts. Highly motivated individuals with a desire to make an impact in the field of cancer genomics are encouraged to apply.
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JOB TITLE: Radiochemistry Postdoctoral Position at the Vancouver Cancer Centre, BC Cancer Agency
POSITION REPORTS TO: Principal Investigator
JOB NUMBER: 2013KSL01
SUMMARY
One postdoctoral position is available starting April 1, 2013 at the Centre of Excellence for Functional Cancer Imaging, BC Cancer Agency for the development of novel radiotracers for cancer imaging with positron emission tomography (PET) and single photon emission computed tomography (SPECT). The postdoctoral candidate will conduct research in the design and synthesis of imaging probes targeting biomarkers overexpressed in cancers. Research activities will involve the production and isolation of radioisotopes, peptide and multi-step organic synthesis, and radiolabeling small molecules, peptides and proteins with PET isotopes (C-11, F-18, Sc-44, Cu-61, Cu-64, Ga-68, Y-86, and Zr-89), and SPECT isotopes (Tc-99m and In-111).
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JOB TITLE: Bioinformatics/Computational Biology Post-Doctoral Position, British Columbia Cancer Agency
POSITION REPORTS TO: Principal Investigator
JOB NUMBER: 2013PS01
SUMMARY
A post-doctoral position is available for a highly motivated bioinformatics expert to join our expanding translational cancer research group engaged in childhood cancer research. The position will be co-supervised by Dr. Poul Sorensen, Department of Molecular Oncology, BC Cancer Research Centre, and Dr. Ryan Morin, Genome Sciences Centre of the BC Cancer Agency. The research group is dedicated to uncovering the molecular basis of childhood cancers, particularly solid tumors, and identifying new diagnostic and predictive markers and developing new tools for assessing these in such diseases.
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JOB TITLE: Research Radiopharmaceutical Chemistry Technician (RA2)
DEPARTMENT: Molecular Oncology, BC Cancer Agency Research Centre
POSITION REPORTS TO: Principal Investigator
JOB NUMBER: 2013FB02
SUMMARY
The Radiopharmaceutical Chemistry Technician (RA2) participates in the research activities on the development of novel radiopharmaceuticals and radiotracer production methods, including the development of a robust quality assurance program for research radiopharmaceuticals. The Technician also participates in writing and developing standard operating procedures for production and quality control. The Technician is also responsible for producing research radiopharmaceuticals to meet the scheduled workload at the PET facility while ensuring that all procedures and protocols for radiopharmaceutical production are followed accurately.
This requires the daily coordination of the production of the required quantity of radioisotopes from the cyclotron, production of radiopharmaceuticals using a manual methods or synthesis modules, completion of required quality controls and documentation of all results. The Technician troubleshoots and resolves technical equipment problems as necessary in order to research patient throughput. Works collaboratively on research activities with external groups as required. The Technician can also be expected to support the clinical production or quality assurance of clinical radiopharmaceuticals when the need arises.
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