If you are interested in pursuing graduate or postdoctoral training in The Department of Molecular Oncology, please send: a cover letter, CV, transcripts, and contact information for 2-3 references to:
Research Assistant/Technician 3 – (MO416)
Reporting to the Chair, Department of Breast & Molecular Oncology, Principal Investigator or designate, the Research Assistant will provide general molecular biology, protein biochemistry and microbiology support within the department of Molecular Oncology. We employ molecular, genomic and genetic techniques to the understanding of cancer; and will maintain and access a number of nucleic and protein analysis platforms. The main focus will be in DNA and RNA preparation and analysis platforms. [read more]
Breast Pathology Fellowship
This unique fellowship is comprised of both clinical and research components in equal parts and provides an opportunity to gain research experience as a fellow. Fellows will divide their time between BC Cancer Agency (BCCA), Mount Saint Joseph and St. Paul’s Hospitals and rotate through the clinical pathology laboratory and the research laboratory at BCCA. Fellows work closely with the breast multidisciplinary team, actively participating in rounds and providing service and consultation to clinicians in matter relating to breast diseases. It is expected that the fellow participates in collaborative research, with an option to conduct individual research, all under the guidance of a faculty member and/or pathologist]. This includes research proposals, submitting abstracts to scientific meetings and preparing manuscripts for publication in peer-reviewed journals. [read more]
Staff Scientist 2
A Staff Scientist 2 position is available in molecular and gynaecologic pathology which encompasses basic, translational and clinical research on the pathogenesis, diagnosis, prevention and treatment of gynecologic cancers. This role is ideal for a highly motivated MD/PhD (preferred) or PhD graduate to join the highly productive and dynamic translational research group. The Staff Scientist will lead and oversee various research projects within the Ovarian Cancer Research (OVCARE) Program of BC. The Staff Scientist is expected to contribute significantly to the scientific development and writing of grant proposals to national and international funding agencies. [read more]
Post-doctoral researcher – Shah Lab
….. to lead key research projects ongoing in the lab of Dr. Sohrab Shah. The PDF should hold a PhD degree in bioinformatics, computer science, statistics or molecular biology and possess exceptional computational skills. The research will focus on one or more of the following topics, all related to analysis of next generation whole genome sequencing data: i) quantifying and modeling tumour evolution; ii) germline genetics and hereditary cancer; iii) alternative splicing in cancer; iv) the mutational landscape of triple negative breast cancer. The PDF will design and carry out experiments to address key questions in the above topics and lead the writing of scientific manuscripts. Highly motivated individuals with a desire to make an impact in the field of cancer genomics are encouraged to apply.
Post-doctoral fellow in the Biochemistry and Chemical Biology of Spliceosome Regulation
The Genome Sciences Centre Department within the British Columbia Cancer Agency in Vancouver, British Columbia, Canada has an opening for a post-doctoral fellow in the laboratory of Dr. Gregg Morin, to study the mechanisms-of-action of pharmacological inhibition of proteins that regulate pre-mRNA splicing. The scientist will join a collaboration with Drs. Samuel Aparicio and Sohrab Shah that is using global genomic technologies to identify changes in alternative splicing due to inhibition of several classes of enzymes that regulate spliceosome function. The objective is to investigate how these enzymes regulate genome-wide spliceosomal function and splice site choice.
The position will perform laboratory research to design and interpret experiments using biochemical, proteomic, molecular and genomic tools to investigate the functional mechanisms of enzyme inhibition on the spliceosome and its regulatory proteins in human cancer cells. The candidate should have experience in ribonucleoprotein biochemistry, mammalian tissue culture, enzymatic assays, recombinant protein purification, molecular biology, and RNAi. Experience in the structure/function analysis of RNPs or enzymes and a comprehensive understanding of splicing and spliceosome function are essential.
The successful scientist will join the laboratory of Dr. Gregg Morin in the Michael Smith Genome Sciences Centre at the BC Cancer Agency. In collaboration with the laboratories of Dr. Samuel Aparicio and Dr. Sohrab Shah, the team has access to exceptional tools for next generation sequencing, bioinformatics, and advanced proteomics.
The Genome Sciences Centre provides a stimulating working environment and is located at the new British Columbia Cancer Research Centre in Vancouver, one of the world’s most livable and attractive cities.
All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.
Additional information can be obtained at www.bcgsc.ca.
Applicants should send a cover letter, curriculum vitae, and names of three referees by email, fax or mail to:
Dr. Gregg B. Morin
Genome Sciences Centre, BC Cancer Agency
675 West 10th Avenue
Vancouver, BC, V6S 1L3, Canada