- Interpretable dimensionality reduction of single cell transcriptome data with deep generative models.
- The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.
- Characteristics and outcome of the COEUR Canadian validation cohort for ovarian cancer biomarkers.
- Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.
May 11, 2015
Research published today by scientists at the BC Cancer Agency in Cancer Cell brings new hope for the treatment of high-risk childhood sarcomas – a type of cancer that has seen almost no treatment improvement in the last 20 years in spite of intense research efforts. Sarcomas are malignant – meaning they are cancerous – […]
April 11, 2013
From the Vancouver Province By Mike Raptis The Province April 7, 2013 A group of Vancouver researchers will be playing a central role in a newly-formed international “pediatric cancer dream team.” The announcement came Sunday during the 2013 annual meeting of the St. Baldrick’s Foundation at the American Association for Cancer Research in Washington, D.C. The […]
December 28, 2011
Dr. David Huntsman and colleagues, including Drs. Aparicio, Sorensen and Shah, have identified mutations in a gene called DICER in rare, seemingly unrelated ovarian, uterine, and testicular cancers. When the group began sequencing the genomes of these and other rare tumours, they expected to find different gene mutations in each form of the disease. However, […]
Posted in Aparicio Lab, Media, News And Events, Papers, Shah Lab, Sorensen Lab | Tagged with Aparicio, BCCF, BCCRC, Cancer, CIHR, Genome BC, GSC, Huntsman, Morin, MSFHR, NEJM, Research, Shah, Sorensen, UBC
June 28, 2011
It’s June? How did that happen?! The first half of 2011 has been a busy and exciting time for the Department of Breast and Molecular Oncology; our scientists have published papers, been awarded grants, and travelled all over the world to speak about their work at conferences. As the summer solstice approaches, it seems like […]
New paper: tumor model systems aid in identifying a critical pathway in ETV6-NTRK3 oncogene driven breast cancers
January 28, 2011
Dr. Cristina Tognon, a Research Scientist in Dr. Sorensen’s laboratory, recently published a new paper in the journal Cancer Research on the role of the insulin receptor and related proteins in secretory breast cancer. “ETV6-NTRK3-Mediated Breast Epithelial Cell Transformation is Blocked by Targeting the IGF1R Signaling Pathway” – Tognon CE, Somasiri AM, Evdokimova VE, Trigo […]