- Interpretable dimensionality reduction of single cell transcriptome data with deep generative models.
- The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.
- Characteristics and outcome of the COEUR Canadian validation cohort for ovarian cancer biomarkers.
- Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.
October 1, 2012
In North America, breast and ovarian cancers are leading causes of morbidity and mortality in women. Tumours arise through continual accrual of mutations in their genomes. The process by which mutations accrue has a random component, thus individual cells within a tumour can acquire different mutations. This diversity within a tumour results in populations of […]
October 28, 2009
We have released a C implementation of the software used in Shah et al (2009) Nature: “Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution.” Please click here for more information.