- Interpretable dimensionality reduction of single cell transcriptome data with deep generative models.
- The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.
- Characteristics and outcome of the COEUR Canadian validation cohort for ovarian cancer biomarkers.
- Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.
June 2, 2016
Building on the world’s largest breast cancer study, BC Cancer Agency scientists map the relationship between cancer mutations and clinical outcomes in 2,433 women. Dr. Samuel Aparicio co-led a study with Dr. Carlos Caldas from Cancer Research UK and these teams have shown that what lies beneath the surface is critical as no two breast […]
November 10, 2014
Dr. Samuel Aparicio, 2014 Aubrey J. Tingle Prize recipient (photo: CNW Group/Canadian Cancer Society (National Office)) Breast cancer researcher Dr. Samuel Aparicio has been named the winner of the fifth annual Aubrey J. Tingle Prize. Created in honour of MSFHR’s founding president & CEO, this award is given to a British Columbia researcher whose work […]
October 1, 2012
In North America, breast and ovarian cancers are leading causes of morbidity and mortality in women. Tumours arise through continual accrual of mutations in their genomes. The process by which mutations accrue has a random component, thus individual cells within a tumour can acquire different mutations. This diversity within a tumour results in populations of […]