- Interpretable dimensionality reduction of single cell transcriptome data with deep generative models.
- The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.
- Characteristics and outcome of the COEUR Canadian validation cohort for ovarian cancer biomarkers.
- Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.
January 12, 2015
Dr. Mardis joined The Genome Institute at Washington University, St. Louis, MO, in 1993. As Director of Technology Development, she helped create methods and automation pipelines for sequencing the human genome. Dr. Mardis has research interests in the application of next-generation sequencing to characterize cancer genomes and transcriptomes, and using these data to support therapeutic decision-making. […]
May 5, 2013
A team co-led by Dr. Samuel Aparicio and scientists from the Cancer Research UK Cambridge Institute (at the University of Cambridge) has published a comprehensive analysis of 1302 breast cancer samples, identifying a key role for microRNAs in controlling tumour progression, and pathogenesis. The study was published in Nature on May 5, 2013. From Nature.com […]