- Interpretable dimensionality reduction of single cell transcriptome data with deep generative models.
- The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.
- Characteristics and outcome of the COEUR Canadian validation cohort for ovarian cancer biomarkers.
- Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.
BC Cancer Agency scientists make internationally significant discovery, mapping the evolution of breast cancer ‘avatars’
December 1, 2014
Vancouver – A just-published paper in the prestigious journal Nature highlights how researchers at the BC Cancer Agency are using human breast cancer ‘avatars’ — models of human breast cancers — to measure how complex cancers develop and change over time. The research is unprecedented because it uses single cancer cells to expose how breast […]
April 28, 2012
Scientists at the BC Cancer Agency and University of British Columbia have identified new breast cancer genes that could change the way the disease is diagnosed and form the basis of next-generation treatments. Researchers have reclassified the disease into 10 completely new categories based on the genetic fingerprint of a tumour. Many of these genes […]
Department of Molecular Oncology study highlights the genetic diversity of triple negative breast cancer
April 5, 2012
A team led by Dr. Sam Aparicio of the Molecular Oncology Department has decoded the genetic make-up of triple negative breast cancer, which could lead to more effective treatment. The study, published online in the international journal Nature, reveals that this form of cancer is not one distinct single entity, but an extremely complex and […]
February 28, 2012
The American Association for the Advancement of Science (AAAS) 2012 Annual Meeting wrapped up at the Vancouver Convention Centre on Monday. This scientific conference – the biggest of its kind – was a great opportunity for local researchers to shine, and two of our department’s Principal Investigators were among the Vancouver-based scientists invited to speak […]
December 28, 2011
Dr. David Huntsman and colleagues, including Drs. Aparicio, Sorensen and Shah, have identified mutations in a gene called DICER in rare, seemingly unrelated ovarian, uterine, and testicular cancers. When the group began sequencing the genomes of these and other rare tumours, they expected to find different gene mutations in each form of the disease. However, […]
Posted in Aparicio Lab, Media, News And Events, Papers, Shah Lab, Sorensen Lab | Tagged with Aparicio, BCCF, BCCRC, Cancer, CIHR, Genome BC, GSC, Huntsman, Morin, MSFHR, NEJM, Research, Shah, Sorensen, UBC