Department of Molecular Oncology
BC Cancer, part of the Provincial Health Services Authority
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Research

Why Biology Matters When it comes to Conquering Breast Cancer

June 2, 2016

Building on the world’s largest breast cancer study, BC Cancer Agency scientists map the relationship between cancer mutations and clinical outcomes in 2,433 women. Dr. Samuel Aparicio co-led a study with Dr. Carlos Caldas from Cancer Research UK and these teams have shown that what lies beneath the surface is critical as no two breast […]

Posted in Aparicio Lab, Media, News And Events, Papers | Tagged with Aparicio, Aparicio Lab, BCCA, BCCF, BCCRC, Breast Cancer, Carlos Caldas, CRUK, Metabric, Research

Open Source Genotyper Software: computational cancer biology in the digital age

May 16, 2016

Roth A, et al. Clonal genotype and population structure inference from single-cell tumor sequencing. Nature Methods. 2016 May 16. doi: 10.1038/nmeth.3867. [Epub ahead of print] Our Nature Methods paper details a new statistical approach for analysing single cell genomics data. The manuscript describes a novel statistical model coupled with a mean field variational inference method […]

Posted in Media, News And Events, Papers, Research Funding, Shah Lab | Tagged with BCCA, BCCF, BCCRC, nature methods, Research, Single cell genotyper, Software, Sohrab Shah, statistics

Scientists map the spread of deadliest ovarian cancer

May 16, 2016

McPherson A, Roth A, Laks E, Masud T, Bashashati A, Zhang AW, Ha G, Biele J, Yap D, Wan A, Prentice L, Khattra J, Mullaly SC, Kalloger S, Karnezis A, Shumansky K, Siu C, Rosner J, Chan HL, Ho J, Melnyk N, Senz J, Yang W, Moore R, Mungall A, Marra MA, Bouchard-Cote A, Gilks […]

Posted in Media, News And Events, Papers, Research Funding, Shah Lab | Tagged with BCCA, BCCF, BCCRC, Cancer Research, nature genetics, ovarian cancer, Research, Sohrab Shah

Dr. Francois Benard and TRIUMF team win NSERC Brockhouse Prize

February 17, 2015

NSERC Brockhouse Prize For CycloMed99 17 February 2015 For their outstanding teamwork in realizing a solution for safe and reliable isotope production for hospitals in Canada, interdisciplinary research team CycloMed99 will be receiving a prestigious national award at a ceremony in Ottawa today. The Honourable David Johnston, Governor General of Canada, will present the NSERC Brockhouse Canada […]

Posted in Benard Lab, Media, News And Events | Tagged with BC Cancer Agency, BCCA, BCCRC, Benard, Brockhouse Prize, Cancer Research, Cyclotron, Francois Benard, Media, Medical Isotopes, NSERC, Radiology, Research, TRIUMF, UBC

Vancouver cancer researchers now key players on ‘dream team’

April 11, 2013

From the Vancouver Province By Mike Raptis The Province April 7, 2013 A group of Vancouver researchers will be playing a central role in a newly-formed international “pediatric cancer dream team.” The announcement came Sunday during the 2013 annual meeting of the St. Baldrick’s Foundation at the American Association for Cancer Research in Washington, D.C. The […]

Posted in Media, News And Events, Sorensen Lab | Tagged with BCCRC, Dream Team, Media, Pediatric Cancer, Research, Sorensen, The Province, UBC

Molecular Oncology researchers at AAAS and in the news

Molecular Oncology researchers at AAAS and in the news

February 28, 2012

The American Association for the Advancement of Science (AAAS) 2012 Annual Meeting wrapped up at the Vancouver Convention Centre on Monday. This scientific conference – the biggest of its kind – was a great opportunity for local researchers to shine, and two of our department’s Principal Investigators were among the Vancouver-based scientists invited to speak […]

Posted in Aparicio Lab, Benard Lab, Media, News And Events | Tagged with AAAS, Aparicio, Benard, Cancer, Research, TRIUMF

Department of Molecular Oncology researchers identify a genetic link between several rare cancers

December 28, 2011

Dr. David Huntsman and colleagues, including Drs. Aparicio, Sorensen and Shah, have identified mutations in a gene called DICER in rare, seemingly unrelated ovarian, uterine, and testicular cancers. When the group began sequencing the genomes of these and other rare tumours, they expected to find different gene mutations in each form of the disease. However, […]

Posted in Aparicio Lab, Media, News And Events, Papers, Shah Lab, Sorensen Lab | Tagged with Aparicio, BCCF, BCCRC, Cancer, CIHR, Genome BC, GSC, Huntsman, Morin, MSFHR, NEJM, Research, Shah, Sorensen, UBC

Research Roundup: Highlights of the year so far

June 28, 2011

It’s June? How did that happen?! The first half of 2011 has been a busy and exciting time for the Department of Breast and Molecular Oncology; our scientists have published papers, been awarded grants, and travelled all over the world to speak about their work at conferences. As the summer solstice approaches, it seems like […]

Posted in Aparicio Lab, Benard Lab, Lin Lab, News And Events, Shah Lab, Sorensen Lab | Tagged with Aparicio, BCCRC, Benard, Huntsman, Research, Shah, Sorensen

New paper: tumor model systems aid in identifying a critical pathway in ETV6-NTRK3 oncogene driven breast cancers

January 28, 2011

Dr. Cristina Tognon, a Research Scientist in Dr. Sorensen’s laboratory, recently published a new paper in the journal Cancer Research on the role of the insulin receptor and related proteins in secretory breast cancer. “ETV6-NTRK3-Mediated Breast Epithelial Cell Transformation is Blocked by Targeting the IGF1R Signaling Pathway” – Tognon CE, Somasiri AM, Evdokimova VE, Trigo […]

Posted in News And Events, Papers, Sorensen Lab | Tagged with BCCRC, News, Research, Sorensen, Tognon

BC Cancer Agency and Pfizer Oncology scientists identify the P-cadherin protein as a prognostic biomarker in breast cancer

October 28, 2010

Scientists from the BC Cancer Agency and Pfizer Oncology have published the first results of their three-year research collaboration. The paper, published in the journal Modern Pathology, analyzed the expression of the P-cadherin protein in breast cancer. P-cadherin is involved in controlling the development and function of the normal mammary gland, but may also play […]

Posted in Aparicio Lab, News And Events, Papers | Tagged with Aparicio, BCCA, BCCRC, Modern Pathology, P-cadherin, Pfizer Canada, Research, Turashvili

Department of Molecular Oncology scientist to tackle medical isotopes problem

November 28, 2009

The world is facing a shortage of the key medical isotope Technetium-99m (Tc-99m). More than 80% of the estimated 1.5 million nuclear medicine procedures performed annually in Canada use radiopharmaceuticals based on this isotope, which is currently produced using nuclear reactors. Together with TRIUMF and other partners, the BC Cancer Agency (BCCA) has received a […]

Posted in Benard Lab, News And Events | Tagged with BCCA, BCCRC, Benard, Research, TRIUMF, UBC

Major breast cancer research breakthrough from the Department of Molecular Oncology and the Genome Sciences Centre

Major breast cancer research breakthrough from the Department of Molecular Oncology and the Genome Sciences Centre

October 7, 2009

Dr. Sam Aparicio of the Department of Molecular Oncology, in partnership with Dr. Marco Marra of the Genome Sciences Centre, has published the first complete genome sequence of a breast cancer. The article is featured on the front cover of this weeks issue of Nature, one of the world’s most prestigious science journals. The study […]

Posted in Aparicio Lab, Media, News And Events, Papers | Tagged with Aparicio, BCCRC, Marra, Nature, Research

Recent Posts

  • Graduate Student Position at the BC Cancer Research Centre, Vancouver, Canada
  • Post-doctoral Fellow – Aparicio Lab
  • Research Assistant / Tech 3 Position
  • Research Animal Technician 2 – Benard Lab

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