- Interpretable dimensionality reduction of single cell transcriptome data with deep generative models.
- The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level.
- Characteristics and outcome of the COEUR Canadian validation cohort for ovarian cancer biomarkers.
- Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.
May 16, 2016
Roth A, et al. Clonal genotype and population structure inference from single-cell tumor sequencing. Nature Methods. 2016 May 16. doi: 10.1038/nmeth.3867. [Epub ahead of print] Our Nature Methods paper details a new statistical approach for analysing single cell genomics data. The manuscript describes a novel statistical model coupled with a mean field variational inference method […]
October 28, 2009
We have released a C implementation of the software used in Shah et al (2009) Nature: “Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution.” Please click here for more information.