Making novel discoveries in the biology underlying normal development and cancer progression.

Our Focus

Ongoing research across a wide spectrum of biomedicine and the life sciences; including biochemistry, stem cell biology, immunology, molecular genetics, molecular medicine and gene therapy.

The Terry Fox Laboratory (TFL) has expertise in diverse research areas, including mammalian systems, normal and malignant mammary tissues, lineage specification in the gut, and yeast genetics. Experimental approaches employed at TFL include genetically engineered models, patient xenograft models, in vitro cell based assays, highly dimension single cell phenotyping, molecular biology and biochemistry, DNA regulation, transcriptomics, epigenetics, and DNA repair. In recent years, TFL has placed emphasis on the development of new technologies and their use to address fundamental questions in the control of cell growth and differentiation, aging, and gene regulation.

Blood Cancer

Working with innovative model systems and patients our research addresses the root causes of leukemias and myeloma and is developing new tools for their diagnosis, characterization and treatment.

Genome Dynamics

Genes influence every aspect of human biology and disease. We are studying how our genes and genomes are faithfully maintained as we age and the complex ways in which they are regulated to control development or are dysregulated during cancer formation.

Stem Cells

Stem cells are critical components in healthy aging and tumour suppression since they enable the development and maintenance of adult tissues. We are working to understand how stem cell properties enable blood, breast and liver development and how these properties are co-opted in cancers.

Immunology

Immunology is the study of the immune system, including its functions, responses to pathogens and foreign substances, and how it protects against disease.  We are investigating the interaction of the immune system with normal and cancer cells to develop novel immunotherapies to use the body’s own immune system to fight cancer.

Research Labs & Principal Investigators

Emeritus Scientists

Scientists In Memorial

News & Events

One More Mile/Team Schnitzel Ride Raises $55,000 for a Great Cause

On Saturday, September 18, 2026, researchers and clinicians from the BC Cancer Research Institute laced up their cycling shoes and hit the road for the One More Mile/Team Schnitzel charity bike ride. 

The team covered an impressive 118 kilometres and raised approximately $55,000 CAD in support of BC Cancer Foundation.

Congratulations to everyone who participated, donated, and cheered the team on. See the group photo above for a look at our riders in action!

Artem Babaian (Mager Lab) defends his PhD thesis entitled “Endogenous Retroviruses Drive Transcriptional Innovation in Human Cancer”

Congratulations to Artem Babaian from the Mager Lab, who successfully defended his PhD thesis entitled “Endogenous Retroviruses Drive Transcriptional Innovation in Human Cancer” on July 30, 2019.

Congratulations to Tabea Stephan (Hoodless Lab) on receiving a Stem Cell Network 2019 Till & McCulloch Meetings travel award.

Tabea has been awarded this competitive Stem Cell Network travel award to attend the 2019 Till & McCulloch Meetings (TMM2019) and present her work on deciphering epigenetic dynamics during in vitro hepatocyte differentiation. TMM2019 will be held in Montréal, Québec, November 4-6, 2019.
 

Recent Publications

Higher Promoter Methylation of the Ubiquitin-Associated and SH3 Domain Containing A (UBASH3A) Gene Is Associated With T-Lymphocyte Ontogeny and Reduced Susceptibility to Early-Onset Sepsis.

The Journal of infectious diseases, 2026
Wang, Ziyi, Amenyogbe, Nelly, Ben-Othman, Rym, Cai, Bing, Lo, Mandy, Idoko, Olubukola T, Odumade, Oludare A, Falsafi, Reza, Blimkie, Travis M, An, Andy, Shannon, Casey P, Montante, Sebastiano, Dhillon, Bhavjinder K, Diray-Arce, Joann, Ozonoff, Al, Smolen, Kinga K, Brinkman, Ryan R, McEnaney, Kerry, Angelidou, Asimenia, Richmond, Peter, Tebbutt, Scott J, Kampmann, Beate, Hancock, Robert E W, Lee, Amy H Y, Levy, Ofer, Kollmann, Tobias R, Martino, David
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Cyt-Geist: Current and Future Challenges in Cytometry: Reports of the CYTO 2025 Conference Workshops.

Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2026
Wallace, Paul K, Jellison, Evan R, Thornton, Sherry, Kluepfel, Kathleen, Back, Jessica, Beadnell, Thomas C, Bebes, Attila, Behrends, Jochen, Belkina, Anna C, Black, Michele, Bogdanoski, Goce, Bollati-Fogolín, Mariela, Bonte, Sarah, Van der Borght, Katrien, Brinkman, Ryan R, Brundage, Kathleen, Bushnell, Tim, Chiu, Daniel T, Chow, Norman, Ciccolella, Christopher O, Cochran, Matthew, Czechowska, Kamila, Dagla, Kleopatra, Daniel, Benjamin, de la Cruz, Gelo, Van Duyse, Julie, Font, Laura Ferrer, Fornas, Òscar, Garcia-Garcia, Sara, Gardner, Rui, Van Gassen, Sofie, Gimenes, Daniel, Grenfell, Richard, Grider-Hayes, Madeline J, Grose, Randall, Hall, Christopher, Hally, Kathryn E, Hameetman, Marjolijn, Hogg, Karen, Houston, Jessica, Irish, Jonathan M, Isterdael, Gert Van, Jaimes, Maria, Janetzki, Sylvia, Kim, Cheryl, Koladiya, Abhishek, Lamote, Jochen, Lannigan, Joanne, Leconte, Julien, Litwin, Virginia, Longhini, Ana, Loof, Nicolas, Lozano-Andrés, Estefanía, Lundsten, Kelly, Mage, Peter, Mair, Florian, Martins, Catarina Gregório, McCausland, Megan, McGuire, Helen M, Meskas, Justin, Murphy, William, Nolan, John, Oliveira, Barbara, Ordoñez-Rueda, Diana, Orlowski-Oliver, Eva, Petersen, Charlotte Christie, Poulton, Nicole J, Putri, Givanna, Quadrini, Karen J, Ramasz, Beata, Ruhrmund, Donald, Singh, Vikas V, Small, Sam J, Smith, Natalie J, Spidlen, Josef, Stegen, Camille, Tak, Tamar, Thompson, Sam, Thomson, Michael, Vocelle, Daniel, Walker, Rachael V, Walsh, Robin E, Wang, Lili, Wang, Yu-Fen, Weglarz, Meredith, Winker, Moritz, Wood, James C S, Woolard, Stacie, Yeh, Nai-Yu, Yuecel, Raif, Rajwa, Bartek
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